Fusion ignition, on the one hand, and particle and power exhaust, on the other, impose often conflicting criteria on the plasma scenario - the former requiring the plasma to be sufficiently heated, fuelled and confined, the latter the helium ash, impurity ions and the total input + fusion power to be removed without undue damage to the reactor itself, specifically its Plasma Facing Components (PFCs) - necessitating an optimisation of the latter to attain the optimum fusion gain for a given reactor design. Foremost among these problems is the issue of power exhaust, including both steady-state and transient heat loads on PFCs. This review examines the various strategies of reducing plasma loads on PFCs at the minimum penalty to the performance of a fusion reactor, specifically ITER, and attempts to quantify the impact of a given PFC limit in terms of the relative change to the fusion gain factor compared to the no-limit value. Preprint of Paper to be submitted for publication in Proceedings of the 18th Plasma Surface Interactions in Controlled Fusion Devices Toledo, Spain ( 26th May 2008 - 30th May 2008)